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目的观察清脑镇痛液的镇痛镇静作用。方法通过热板法和电刺激法观察镇痛作用;通过对自主活动和阈下催眠剂量戊巴比妥钠的协同作用的影响,观察镇静作用。结果高剂量清脑镇痛液可显著延长小鼠对热刺激的痛阈(P<0.01),延长对电刺激的痛阈(P<0.05),并可减少小鼠的自主活动数(P<0.05),使催眠剂量戊巴比妥钠的小鼠入睡只数增多(P<0.05)。结论清脑镇痛液具有一定的镇痛镇静作用。
Objective To observe the analgesic and sedative effects of Qingnao analgesic. Methods The analgesic effect was observed by hot plate method and electrical stimulation. The sedation effect was observed by the synergistic effect of spontaneous activity and subthreshold hypnosis dose of sodium pentobarbital. Results High doses of Qingnao analgesia could prolong the pain threshold of thermal stimulation (P <0.01), prolong the pain threshold (P <0.05) and decrease the number of spontaneous activity of mice (P < 0.05). The hypnotic dose of sodium pentobarbital mice only increased the number of falling asleep (P <0.05). Conclusions Qingnao analgesic has certain analgesic and sedative effects.