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【化学名】1,2-双(4-吗啉甲撑-3,5-二氧哌嗪-1)-乙烷【结构式】【作用特点】本品为我国设计合成的一种新抗肿瘤药,对多种实验性动物肿瘤有明显疗效,能抑制小鼠肉瘤S37、S180的生长,抑瘤率达99％以上。本品可减少肿瘤四周血管形成,防止肿瘤转移。动物试验表明本品对放疗有增效作用,与放疗合用则抗肿瘤作用明显增强。放射自显影法显示,本品对S期有抑制作用,故能抑制DNA的生物合成。溶血素试验结果表明,它对体液免疫有轻度抑制作用,但不抑制细胞免疫。本品口服易吸收,5分钟后即可在血中测出,分次小剂量间歇给药吸收则更好,其血
【Chemical Name】 1,2-bis (4-morpholine methyl -3,5-dioxopiperazine-1) - ethane 【Structure】 【Features】 This product is designed and synthesized in our country a new anti-tumor Medicine, a variety of experimental animal tumors have a significant effect, can inhibit the growth of mouse sarcoma S37, S180, tumor inhibition rate of 99%. This product can reduce the formation of blood vessels around the tumor to prevent tumor metastasis. Animal experiments show that this product has a synergistic effect of radiotherapy, radiotherapy and anti-tumor effect was significantly enhanced. Autoradiography shows that this product has an inhibitory effect on the S phase, it can inhibit DNA biosynthesis. Hemolysin test results show that it has a mild humoral immune suppression, but does not inhibit cellular immunity. This product is easy to absorb oral, 5 minutes after the measured in the blood, intermittent small doses of intermittent drug absorption is better, the blood