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原发性或继发性局灶性节段性肾小球硬化症(FS-GS)是一种常见的肾小球损害,常与蛋白尿及肾病综合征相联系。原发性FSGS已被认为是由未知的循环因子所引起,而继发性FSGS似乎是肾单位减少的一种适应性改变。老年患者中动脉硬化性肾血管疾病(RVD)更多地被发现,且严重的单侧或双侧肾动脉狭窄常导致肾缺血和肾单位功能下降。为探讨老年患者中RVI)是否易于发展为FSGS作者回顾分析了90～95年间研究所病理证实为FSGS的病例。 方法:选择了59例活检病理证实的FSGS病例,分析了所有临床资料,组织学材料,并用放射学检查来评估肾血管功能。
Primary or secondary focal segmental glomerulosclerosis (FS-GS) is a common glomerular lesion often associated with proteinuria and nephrotic syndrome. Primary FSGS has been thought to be caused by an unknown circulatory factor, whereas secondary FSGS appears to be an adaptive change in nephron reduction. Arteriosclerotic renal vascular disease (RVD) is more commonly found in elderly patients and severe unilateral or bilateral renal artery stenosis often leads to renal ischemia and decreased nephron function. To explore the elderly patients with RVI) is easy to develop into FSGS The authors reviewed the 90 to 95 years of the Institute of pathology confirmed as FSGS cases. METHODS: Fifty-nine FSGS cases confirmed by biopsy were selected and all clinical and histological materials were analyzed. Radiological examinations were performed to assess renal vascular function.