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研究表明，超氧化物歧化酶（ＳＯＤ）活性对平阳霉素在体外和体内的抗癌作用有明显的影响．为了进一步探讨ＳＯＤ活性与平阳霉素抗癌作用的机理，本实验运用图象分析方法连续一周动态地观察了ＳＯＤ活性与平阳霉素对肺癌细胞的ＤＮＡ福尔根光密度、Ｓ期细胞比率、细胞增殖指数、核面积的影响，结果发现，降低ＳＯＤ活性可明显增强平阳霉素对肺癌细胞的作用，使癌细胞的Ｓ期细胞比率和增殖指数明显降低；而提高ＳＯＤ活性则明显降低了平阳霉素的作用．另外，本文还就实验中发现的受药物作用后的癌细胞的核面积和ＤＮＡ福尔根光密度的变化作了讨论．
Studies have shown that superoxide dismutase (SOD) activity of pingyangmycin in vitro and in vivo anticancer effects have a significant effect. In order to further explore the mechanism of SOD activity and Pingyangmycin anticancer effect, we used image analysis method to dynamically observe the activity of SOD and phosphorylation of DNA of Forland root in lung cancer cells, the ratio of S phase cells, Cell proliferation index, nuclear area, the results showed that reducing SOD activity can significantly enhance the effect of pingyangmycin on lung cancer cells, so that the S phase cell ratio and proliferation index of cancer cells decreased significantly; while increased SOD activity was significantly reduced Pingyang The role of mycophenolate. In addition, we also discussed the change of the nuclear area of the cancer cells and the DNA formalin density found in the experiments.