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烟浪丁又名硝烟脂,国际上最早研究开发于1975年,国内1984年之后陆续有近十几个单位进行研制工作。1986年3月陕西省医药科研试验厂研制成功升正式投入生产。 烟浪丁具有选择性、和剂量依存性地扩张冠状动脉血管。使冠状动脉血流量增加一倍也不影响心脏功能,其作用机理主要由于膜的过极化和钾通透性增强,使冠状动脉扩张引起心肌供氧量增加。大量试验证实,烟浪丁具有迅速扩张冠状动脉、增加营养血流量的作用,持续时间长达3小时,还能使部分阻塞的冠状动脉血流量增加,可见心电图S—T段明显改善,缺血区的
Also known as the nicotine cigarette smoke fat, the earliest international research and development in 1975, after 1984, one after another domestic nearly a dozen units to carry out research and development work. March 1986 Shaanxi Province Pharmaceutical Research and Development Experimental Factory successfully developed or formally put into production. Smoke waves are selective and dilate coronary vessels in a dose-dependent manner. So that double the coronary blood flow does not affect cardiac function, its mechanism of action mainly due to membrane polarization and potassium permeability increased, the expansion of coronary artery caused by increased myocardial oxygen supply. A large number of experiments confirmed that Yan Lang Ding has the rapid expansion of the coronary artery to increase the role of nutritional blood flow, duration up to 3 hours, but also to some of the obstruction of the coronary blood flow increased, visible ECG S-T segment was significantly improved, ischemia District