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麻风病是在皮肤巨噬细胞和周围神经雪旺氏细胞内寄生的麻风分枝杆菌引起的疾病。其临床表现决定于宿主对抗原的免疫应答。瘤型麻风细胞介导免疫(CMI)缺陷并伴有γ干扰素(IFN-γ)产生减少,导致巨噬细胞不能被充分激活。由于麻风病具有临床和免疫上的多样性,因此麻风病可作为研
Leprosy is a disease caused by M. leprae that is parasitic in skin macrophages and peripheral Schwann cells. Its clinical manifestations depend on the host’s immune response to the antigen. Tumor-type leprosy-mediated immune deficiency (CMI) defects accompanied by reduced production of interferon-gamma (IFN-γ), resulting in macrophages can not be fully activated. Because of the clinical and immunological diversity of leprosy, leprosy can serve as research