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目的探讨同型半胱氨酸(Hcy)与纤维蛋白原(FIB)在缺血性心肌病(ICM)和扩张型心肌病(DCM)鉴别诊断中的应用价值。方法分别检测64例ICM患者(ICM组)、55例DCM患者(DCM组)、60例冠脉造影检查和超声心动图检査正常者(对照组)血清中Hcy水平和血浆FIB水平,比较各组患者之间Hcy与FIB水平的差异。结果 ICM组与DCM组血清Hcy水平和血浆FIB水平差异有统计学意义(P<0.05)。结论 Hcy和FIB水平在ICM患者中明显升高,在ICM和DCM鉴别诊断中具有重要应用价值。
Objective To investigate the value of homocysteine (Hcy) and fibrinogen (FIB) in the differential diagnosis of ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM). Methods Sixty-four patients with ICM (ICM group), 55 DCM patients (DCM group), 60 patients with normal controls (group C) Differences in Hcy and FIB levels between groups of patients. Results There was a significant difference in serum Hcy level and plasma FIB level between ICM group and DCM group (P <0.05). Conclusion The levels of Hcy and FIB are significantly elevated in patients with ICM, which has important value in the differential diagnosis of ICM and DCM.