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免疫球蛋白及补体(C_3)的沉淀物在系统性红斑性狼疮(SLE)患者不仅可以在皮损的表皮—真皮联结处发现免疫球蛋白(Ig)及/或补体(C_3)的沉淀物,而且也可见于临床上正常的皮肤。本文报导在SLE以及盘状红斑性狼疮(DLE)患者的正常皮肤区均发现上述沉淀物。采用异硫氰酸荧光素(FITC)标记的对人γ,μ及α链及C_3的β-1c特异的兔IgG于冰冻组织切片上进行免疫组织化学染色,在荧光显微镜下进行观察。共观察97例患者及67例对照者。前者SL E64
Immune Globulin and Complement (C_3) Precipitates Patients with systemic lupus erythematosus (SLE) not only find immunoglobulin (Ig) and / or complement (C_3) precipitates at the epidermal-dermal junction of the lesions, It is also found in clinically normal skin. This article reports the discovery of the above deposits in the normal skin area of patients with SLE and discoid lupus erythematosus (DLE). Immunofluorescence staining was performed on frozen tissue sections using fluorescein isothiocyanate (FITC) -tagged human γ, μ and α chains and C_3 β-1c-specific IgG, and observed under a fluorescence microscope. A total of 97 patients and 67 controls were observed. The former SL E64