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1.合成了8-(β-氨乙基巯基)及8-(β-胍乙基巯基)咖啡碱与它们的类似物8-(β-巯乙基氨基)及8-(β-S-异硫脲基乙基氨基)咖啡碱。 2.由巯基化合物与β-溴乙胺溴氢酸盐直接反应,制备了具有β-氨乙基巯基的苯并咪唑、甲基咪唑、苯并咪唑及咪唑啉等衍生物。
1. Synthesis of 8- (β-aminoethylmercapto) and 8- (β-guanidiniumthylmercapto) caffeine with their analogues 8- (β-mercaptoethylamino) and 8- Thioureidoethylamino) caffeine. By thiol compounds and β-bromoethylamine hydrobromide direct reaction, prepared with β-aminoethylmercaptobenzimidazole, methylimidazole, benzimidazole and imidazoline and other derivatives.