论文部分内容阅读
为了判定局部应用NSAIDs对急性和慢性疼痛疾病治疗的有效性和安全性,采取随机对照试验的定量方法对86项研究中的10 160例病人的主要结果测定进行评述。 主要结果测定包括至少减轻50％左右疼痛的有效治疗以及在治疗中出现的局部和全身性副作用。在治疗1周时对急性疼痛和在治疗2周时对慢性疼痛分析其相对效用和需要治疗的次数。由于结果是非齐性的,故采用随机效果模式从安慰剂对照去获取疼痛数据,以计算出相对效用(95％可
To determine the efficacy and safety of topical NSAIDs in the treatment of acute and chronic pain diseases, a randomized controlled trial of quantitative methods was used to review the primary outcome measures of 10,160 patients in 86 studies. The primary outcome measures include effective treatment that ameliorates at least about 50% of pain and the local and systemic side effects that occur during treatment. Chronic pain was analyzed for the relative efficacy and the number of treatments needed for acute pain at 1 week of treatment and at 2 weeks of treatment. Since the results were non-homogeneous, the pain data were obtained from the placebo control using a random effect model to calculate the relative utility (95%