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胎儿苯妥英钠综合征是指孕妇有服用苯妥英钠史,引起胎儿畸形。主要表现为头面部、肢体畸形,内脏缺损,生长及智力障碍等。其发生率约10.5％。笔者所见一例报告如下。男,9岁,因自幼至今间断抽搐、智力低下,近两月伴呕吐入院。患儿于生后10天无明显诱因开始频繁抽搐,4个月时静注钙剂后,抽搐有所减轻,但仍有1～2次/日,近一年来不规则服用苯妥英钠。智力低于同龄儿,语言能力差,仅能听懂日常生活用
Fetal phenytoin syndrome is that pregnant women have taken phenytoin sodium history, causing fetal malformations. Mainly for the head and face, limb deformities, visceral defects, growth and mental retardation. The incidence of about 10.5%. The author sees a case report as follows. Male, 9 years old, because of intermittent seizures since childhood, mental retardation, with vomiting admitted to hospital in the past two months. Children in 10 days after birth, no obvious incentive to start frequent convulsions, 4 months after intravenous calcium, convulsions have been reduced, but there are still 1 or 2 times / day in the past year irregularly taking phenytoin sodium. Intelligence below age children, poor language skills, can only understand daily life