MicroRNA-31 expression in colorectal serrated pathway progression

• 作 者: Hironori Aoki Katsuhiko Nosho
• 机 构: CenterforGastroenterology,DepartmentofGastroenterology,DepartmentofPathology,DepartmentofMolecularBi
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2014年34期
• 关键词: BRAF COLORECTAL CARCINOMA MicroRNA-31 MLH1 Microsa BRAF Colorectal carcinoma M
• 基金项目: Japan Society for the Promotion of Science(JSPS)Grant-in-Aid for Scientific Research,grant No.23790800(to Nosho K),A-STEP(Adaptable and Seamless Technology Transfer Program through Target-driven R and

MicroRNAs have been increasingly recognized as useful biomarkers for colorectal cancers(CRC).We have recently observed that microRNA-31(miR-31)expression is associated with BRAF mutation and prognosis in CRC.Moreover,high miR-31 expression is frequently d