论文部分内容阅读
目的:探讨陕西地区人群克罗恩病发病的危险因素。方法:采用病例对照研究,选择2009年1月～2010年12月在我院就诊的64例克罗恩病患者和64例健康对照者为研究对象,通过问卷的方式进行调查,调查内容包括饮食习惯、受教育情况、职业、家庭卫生情况、吸烟、母乳喂养、肠道疾病家族史、感染性肠病史、阑尾切除术、麻疹等内容,采用条件logistic回归分析影响陕西地区人群克罗恩病发病的危险因素。结果:64例克罗恩病患者及64例配对的健康对照者均完成问卷调查,多因素条件logistic回归分析结果显示,人均居住面积(大)(OR 0.4003,95%CI 0.1577,1.0165)、饮茶(OR 0.2597,95%CI 0.0662,1.0184)、油炸食品(OR3.1465,95%CI 1.2841,7.7101)、口服避孕药(OR 5.4500,95%CI 0.8400,35.1158)是陕西地区人群克罗恩病发病的危险因素。结论:油炸食品、服避孕药可能为陕西地区人群克罗恩病发病的危险因素,人均居住面积(大)、饮茶可能为陕西地区人群克罗恩病发病保护因素。
Objective: To explore the risk factors of Crohn’s disease in Shaanxi population. Methods: A case-control study was conducted. Sixty-four patients with Crohn’s disease and 64 healthy controls who were treated in our hospital from January 2009 to December 2010 were selected as the research subjects. The questionnaire was used to investigate the contents of the survey including diet Smoking, breastfeeding, family history of intestinal diseases, history of infectious bowel disease, appendectomy, measles and so on, using conditional logistic regression analysis to analyze the incidence of Crohn’s disease in Shaanxi population Risk factors. Results: Sixty-four patients with Crohn’s disease and 64 matched healthy controls completed the questionnaire. Multivariate conditional logistic regression analysis showed that the average per capita living space (OR 0.4003, 95% CI 0.1577, 1.0165) and drinking (OR 0.2597, 95% CI 0.0662, 1.0184), fried foods (OR 3.1465, 95% CI 1.2841, 7.7101) and oral contraceptives (OR 5.4500, 95% CI 0.8400, 35.1158) Disease risk factors. Conclusion: Fried foods and contraceptives may be the risk factors for Crohn ’s disease in Shaanxi area. The per capita living space (large), drinking tea may be the protective factor for the incidence of Crohn’ s disease in Shaanxi population.