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目的为探讨儿童血铅与其他五种元素的相关性,以便科学合理地指导儿童铅中毒防治的营养干预措施。方法采用原子吸收分光光度仪测定血铁、锌、钙、镁、铜,采用阳极溶出电解仪测定全血铅;对本地区2010~2012年间2 710例学龄前儿童的检测资料进行分析。结果(1)儿童铅中毒发生率为9.37%,以1~7岁儿童居多;(2)本地学龄前儿童血清钙、铁和锌三种元素的缺乏率较高。儿童铅、铁、锌含量随着年龄的增长呈上升趋势,钙呈下降趋势。除血铅外其他五种元素在性别上无差异;(3)正常儿童的血铅水平与钙呈负相关,而与铁、锌成正相关;儿童铅中毒时血铅与锌呈负相关。结论在儿童铅中毒的防治过程中应注意钙和锌的补充。
Objective To explore the correlation between blood lead in children and other five elements in order to guide scientific and rational nutrition interventions for prevention and control of lead poisoning in children. Methods The determination of blood iron, zinc, calcium, magnesium and copper by atomic absorption spectrophotometer was used to determine the content of lead in whole blood. The data of 2 710 preschool children from 2010 to 2012 in this area were analyzed. Results (1) The incidence of lead poisoning in children was 9.37%, mostly children aged from 1 to 7 years old. (2) The local lack of calcium, iron and zinc in preschool children was high. Children lead, iron, zinc content increased with age, calcium showed a downward trend. There was no difference in gender among the five elements except blood lead; (3) The blood lead level in normal children was negatively correlated with calcium, but positively correlated with iron and zinc; while the lead poisoning in children was negatively correlated with zinc. Conclusion In the prevention and treatment of childhood lead poisoning, we should pay attention to the supplement of calcium and zinc.