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目的:研究分析妊娠早期妇女骨密度的变化情况,为临床合理补钙提供科学依据。方法:随机选择126例深圳居住的正常妊娠早期妇女为研究对象,按孕周不同分为两组,Ⅰ组为4～7周,Ⅱ组为8～11周,用定量超声骨密度仪(QUS)测定受检者足跟部骨密度(BMD)值;随机选择80例正常健康非妊娠妇女作为对照组。结果:妊娠早期两组骨密度值均较正常组稍高,但各组之间两两比较差异无统计学意义(P>0.01)。结论:妊娠早期妇女骨密度值并没有明显下降,妊娠早期是否需要补钙尚需进一步探讨。
OBJECTIVE: To study and analyze the changes of bone mineral density (BMD) in early pregnancy and to provide a scientific basis for clinical reasonable calcium supplement. Methods: A total of 126 early pregnant women living in Shenzhen were selected randomly as the study group, divided into two groups according to gestational age: Ⅰ to 4 to 7 weeks and Ⅱ to 8 to 11 weeks. Quantitative ultrasound bone densitometry (QUS ) Were used to measure the heel bone mineral density (BMD) of the subjects. Eighty healthy, non-pregnant women were randomly selected as the control group. Results: The BMD of both groups was slightly higher than that of the normal group in the first trimester of gestation, but there was no significant difference between the two groups (P> 0.01). Conclusion: There is no obvious decrease of BMD in early pregnancy, and the need of calcium supplement in early gestation needs to be further explored.