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目的 :观察石化企业老职工心脑血管病危险因素强化干预所带来的益处。方法 :1990年茂名石化公司进行全员大体检 ,5 0岁以上在职职工中有高血压、高血脂共 15 5 2人 ,随机分为干预组 (775人 )和对照组 (777人 ) ,干预组应用钙离子拮抗剂和 (或 )血管紧张素转换酶抑制剂控制高血压 ,应用血脂调节药物控制高脂血症。比较两组在 10 a间出现心脑血管终末事件。结果 :干预组发生心脑血管终末事件比对照组明显减少 (P<0 .0 1)。结论 :对石化行业有心脑血管疾病危险因素者积极干预可显著降低心脑血管终末事件的发生率
OBJECTIVE: To observe the benefits of intensive interventions for risk factors of cardiovascular and cerebrovascular diseases among veteran workers in petrochemical enterprises. Methods: In 1990, Maoming Petrochemical Company conducted a general medical examination. A total of 15 5 2 high-blood pressure and high blood lipids were included in the working staff over the age of 50, and randomly divided into intervention group (775) and control group (777) Group application of calcium antagonists and (or) angiotensin-converting enzyme inhibitors to control hypertension, the application of lipid-lowering drugs to control hyperlipidemia. Compare the two groups in the 10-year cardiovascular events. Results: The incidence of cardiovascular events in the intervention group was significantly lower than that in the control group (P <0.01). Conclusion: Positive intervention in risk factors of cardiovascular and cerebrovascular diseases in petrochemical industry can significantly reduce the incidence of cardiovascular events