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100年来的文献上曾经提示糖尿状态可以使糖尿病人出现内耳功能障碍,但对糖尿病与内耳功能障碍二者之间的关系还要进一步研究.糖尿病的并发症涉及到真皮、视网膜和肾脏,它们的共同基础是微血管病变,这种微血管病变也是内耳迷路功能障碍的主要病因.本文是用定量的光学显微镜和电子显微镜技术观察长期糖尿病鼠的圆囊和椭圆囊斑区,以便更好地了解长期糖尿病对内耳结构的影响.选用年龄为一个月的雌鼠28只,在一个半月时由鼠的尾部静脉注入Streptozotocin造成糖尿病,19只鼠做为对照组.做血中葡萄糖分析,灌注动物,固定组织,进行光学和电子显微镜
The literature over the past 100 years has suggested that diabetes can cause diabetic patients with dysfunction of the inner ear, but the relationship between diabetes and dysfunction of the inner ear needs further study.The complications of diabetes related to the dermis, retina and kidney, their The common basis is microangiopathy, which is also the main cause of dysfunction of the inner ear.In this paper, quantitative optical and electron microscopy were used to observe the pericardium and the oval plaque in long-term diabetic mice in order to better understand the long-term diabetes On the structure of the inner ear.Select the age of one month 28 females, one and a half months from the tail vein of mice injected Streptozotocin caused diabetes, 19 rats as a control group.Do blood glucose analysis, perfusion of animals, fixed tissue , Carried out optical and electron microscopy