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目的观察小剂量阿替洛尔联合螺内酯治疗慢性心力衰竭的临床效果。方法选取医院收治的慢性心力衰竭患者82例为研究对象,随机分为2组,每组各41例。2组患者均给予常规治疗,在此基础上,对照组采用小剂量阿替洛尔治疗,观察组采用小剂量阿替洛尔联合螺内酯治疗,比较分析2组患者的临床疗效。结果观察组患者收缩压、舒张压和心电图检查结果均优于对照组;观察组总有效率高于对照组,2组比较差异均有统计学意义(P<0.05或P<0.01)。结论在临床上采用小剂量阿替洛尔联合螺内酯治疗慢性心力衰竭患者,具有较好的临床效果。
Objective To observe the clinical effect of low-dose atenolol combined with spironolactone in the treatment of chronic heart failure. Methods Totally 82 patients with chronic heart failure who were treated in hospital were selected as the research object and randomly divided into 2 groups, 41 cases in each group. Two groups of patients were given conventional treatment, on this basis, the control group with a small dose of atenolol treatment, the observation group with a small dose of atenolol and spironolactone treatment, comparative analysis of two groups of patients with clinical efficacy. Results The systolic blood pressure, diastolic blood pressure and electrocardiogram in the observation group were better than those in the control group. The total effective rate in the observation group was higher than that in the control group. There was significant difference between the two groups (P <0.05 or P <0.01). Conclusion The clinical use of low-dose atenolol combined with spironolactone in patients with chronic heart failure has a good clinical effect.