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目的 探讨耐甲氧西林金黄色葡萄球菌 (MRSA)的分子流行病学特点。方法 采用脉冲场凝胶电泳 (PFGE)技术对我院在 2 0 0 1年 6月～ 2 0 0 2年 4月临床分离的 5 0株MRSA作同源性分析。结果 5 0株MRSA的PFGE图谱分为 6个组 (A～F型 )。以A型 (2 7株 )、B型 (10株 )、C型 (10株 )流行为主。 5 0株MRSA中共有 17株和重症监护室 (ICU)相关 ,占 34%。流行菌株在各病房之间传播。结论 ICU是MRSA的高发区域和疫源地 ,神经外科、肝胆胰外科和干部病房中MRSA的分离率也较高。在同一病人不同时间不同部位所采集的菌株同源性不尽相同
Objective To investigate the molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA). Methods The homology analysis of 50 MRSA isolates clinically isolated in our hospital from June 2001 to April 2002 was performed by using pulsed-field gel electrophoresis (PFGE). Results The PFGE profiles of 50 MRSA strains were divided into 6 groups (type A to F). A type (27 strains), B type (10 strains), C type (10 strains) prevalence. A total of 17 out of 50 strains of MRSA were associated with intensive care unit (ICU), accounting for 34%. Popular strains spread between wards. Conclusion ICU is a high incidence area and foci of MRSA. The isolation rate of MRSA in neurosurgery, hepatobiliary and pancreatic surgery and cadre wards is also higher. In the same patient at different times at different parts of the collected strains of homology is not the same