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本文通过给予大鼠不同剂量的苦参、仙鹤草观察含药血清对肝癌腹水癌细胞体外生长的影响，探索该方法中制备含药血清过程的给药剂量。结果发现，以参考公式（给药剂量等于临床用量乘以动物等效面积系数再乘以培养基内血清稀释度）计算给药剂量得到的含药血清对肿瘤细胞体外生长有抑制作用（Ｐ＜０．０５），而比以参考公式计算给药剂量小一倍得到的含药血清有明显作用（Ｐ＞０．０５）。以上实验结果提示以上述的参考公式计算给药剂量来制备含药血清具有一定的合理可行性。
In this paper, different doses of Sophora flavescens and Agrimony were used to observe the effects of medicated serum on the growth of hepatoma ascites carcinoma cells in vitro and to explore the dosage of this method. The results showed that, with the reference formula (dose is equal to the clinical dosage multiplied by animal equivalent area factor multiplied by the serum dilution) calculated serum dose of the drug-containing serum on the growth of tumor cells inhibited (P < 0.05), but it was significantly higher than that of drug-containing serum (P> 0.05), which was smaller than that calculated by reference formula. The above experimental results suggest that with the above reference formula to calculate the dose to prepare medicated serum has a certain reasonable feasibility.