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肾性骨营养不良是慢性肾衰竭的主要并发症之一。许多尿毒症患者,尤其是长期接受血液透析的病人,由于体内钙磷代谢的紊乱,会出现骨痛、骨折等现象。抑制这种病人的继发性甲状旁腺机能亢进,可消除这些代谢紊乱。为此,可口服1,25—二羟胆钙化醇[1,25(OH)_2D_3]并佐以磷结合剂治疗。但当病人血中甲状旁腺激素水平很高时,此法效果不佳,Slatoplsby等用静脉注射大剂量
Renal osteodystrophy is one of the major complications of chronic renal failure. Many uremic patients, especially long-term hemodialysis patients, due to the disorder of calcium and phosphorus metabolism, there will be bone pain, fractures and so on. Suppressing this patient’s secondary hyperparathyroidism can eliminate these metabolic disorders. To this end, 1,25-dihydroxycholecalciferol [1,25 (OH) _2D_3] can be taken orally and treated with phosphorus-binding agent. However, when the patient’s blood levels of parathyroid hormone is high, this method ineffective, Slatoplsby other intravenous boluses