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了解我市健康儿童白喉免疫水平，保证健康儿童的白喉免疫接种率，为预防并最终消灭白喉提供流行病学依据。方法：１９９９年在我市采取分层整群抽样方法随机抽取了５８６名健康儿童作为调查分析对象，其中男性２９６名，女性２８９名，以锡克氏试验作为判断免疫水平标准。结果：男女阴性率分别为８４．１２％、８２．０１％，Ｘ２＝０．４６５１２７４，Ｐ＞０．０５，其中＜７岁组１６８例，７～１０岁组：１９７例。＞１０岁组１４６例，阴性率分别为８５．１２％、８３．８％、８０．２２％，Ｘ２＝１．６４９５８３，Ｐ＞０．０５。男女阴性率以及各年龄组阴性率均无显著性差异。阴性率随着年龄下降而上升。结论：我市儿童白喉免疫水平呈上升趋势，但从最低阴性率来看，将近有二十个百分点的儿童易感，这与消灭白喉的水平还有相当的距离，须进一步加强计划免疫工作。
Understand the level of diphtheria immunity in healthy children in our city, ensure the diphtheria immunization rate in healthy children and provide epidemiological basis for the prevention and eventually elimination of diphtheria. Methods: In 1999, stratified cluster sampling method was adopted in our city to randomly select 586 healthy children as the investigation and analysis objects, including 296 males and 289 females, taking Skeletal test as the criteria for judging immunity. Results: The male and female negative rates were 84.12%, 82.01%, X2 = 0.4651274, P> 0.05, of which 168 were <7 years old and 197 cases were aged 7-10 years old. There were 146 cases> 10 years old, the negative rates were 85.12%, 83.8%, 80.22%, X2 = 1.649583, P> 0.05. There was no significant difference between male and female negative rates and the negative rates of all age groups. Negative rates increased with age. Conclusion: The level of diphtheria immunity in our city is on the rise. However, from the lowest negative rate, nearly 20% of children are susceptible. This is still a considerable distance from eliminating diphtheria and further strengthening planned immunization.