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测定48例肺癌患者血清骨钙素的浓度。结果表明，肺癌患者血清骨钙素浓度比正常人明显升高，约为正常人的1．8倍。小细胞肺癌血清骨钙素水平最高。肺癌伴骨转移者血清骨钙素浓度明显低于无骨转移者。肺癌患者血清骨钙素浓度与CEA呈明显正相关。
The serum osteocalcin concentration was determined in 48 patients with lung cancer. The results showed that the concentration of serum osteocalcin in lung cancer patients was significantly higher than normal people, about 1.8 times that of normal people. The serum osteocalcin level was highest in small cell lung cancer. Serum osteocalcin concentrations in lung cancer patients with bone metastases were significantly lower than those without bone metastases. There was a positive correlation between serum osteocalcin concentration and CEA in patients with lung cancer.