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目的 :探讨治疗复发性十二指肠溃疡的新方法 ,观察清创术治疗十二指肠溃疡的愈合率及其复发率。方法 :选择反复发作的十二指肠溃疡 10 0例 ,随机分为两组 ,治疗组采用胃镜下清创术后服用雷尼替丁、得乐冲剂、甲消唑治疗 ,对照组织只服药物治疗。治疗后 4周复查胃镜。观察病人十二指肠溃疡的愈合率及其半年内、一年内的复发率。结果 :治疗组 4周溃疡愈合率为 94 % (47/5 0 ) ,对照组为 78% (39/5 0 ) ;半年内复发率 :治疗组为 8.5 % (4/47) ,对照组为 30 % (13/39) ;1年内复发率 :治疗组为 13.2 % (6 /47) ,对照组为 4 3.7% (16 /39)。结论 :胃镜下清创术配合药物治疗复发性十二指肠溃疡不仅能提高治愈率 ,而且能明显降低复发率 ,值得临床进一步推广。
Objective: To explore a new method of treating recurrent duodenal ulcer and to observe the healing rate and the recurrence rate of debridement in treating duodenal ulcer. Methods: One hundred and ten patients with recurrent duodenal ulcer were randomly divided into two groups. The patients in the treatment group were treated with ranitidine, Detox and metozole, treatment. Gastroscope was reviewed 4 weeks after treatment. Observe the healing rate of patients with duodenal ulcer and the recurrence rate in one year within six months. Results: The healing rate of ulcer in the treatment group was 94% (47/5) in 4 weeks and 78% (39/5 0) in control group. The recurrence rate within 6 months was 8.5% (4/47) in the treatment group and 30% (13/39). The relapse rate in one year was 13.2% (6/47) in the treatment group and 43.7% (16/39) in the control group. Conclusion: Endoscopic debridement combined with drug treatment of recurrent duodenal ulcer can not only improve the cure rate, but also significantly reduce the recurrence rate, it is worth further clinical promotion.