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目的 明确弥散加权成像 (DWI)对超急性期脑梗塞的诊断价值 ,探讨DWI缺血损伤体积与预后的关系。方法 将 2 1例患者分为超急性期、急性期、亚急性期、慢性期。分别计算出各期的DWI及T2 WI上缺血损伤体积和临床评分。结果 DWI对识别超急性期脑梗塞缺血损伤达 10 0 %。急性期、亚急性期、慢性期T2 WI缺血损伤体积比DWI的大 (P <0 .0 1)。超急性期DWI缺血损伤体积与慢性期临床评分有显著相关性 (P <0 .0 5 )。超急性期、慢性期DWI缺血损伤的体积与相应的临床评分有显著相关 (P <0 .0 5、P <0 .0 1)。结论 DWI对识别超急性期梗塞的缺血损伤优于常规磁共振扫描。DWI缺血损伤的大小对预测超急性期脑梗塞患者的临床结果具有潜在意义
Objective To investigate the diagnostic value of diffusion-weighted imaging (DWI) for hyperacute cerebral infarction and to explore the relationship between the volume of DWI and prognosis. Methods Twenty-one patients were divided into two groups: hyperacute phase, acute phase, subacute phase, and chronic phase. The volume and clinical score of ischemic injury on DWI and T2WI were calculated at each stage. Results DWI was used to identify ischemic injury of hyperacute cerebral infarction up to 10%. Acute phase, subacute phase, chronic WIW ischemic injury volume than DWI (P <0.01). There was a significant correlation between the hyperacute phase DWI volume and the clinical score of chronic phase (P <0.05). The volume of hyperacute and chronic ischemic insult in DWI was significantly correlated with the corresponding clinical scores (P <0.05, P <0.01). Conclusion DWI is better than conventional MRI in identifying ischemic injury of hyperacute infarction. The magnitude of ischemic injury in DWI is potentially useful in predicting the clinical outcome of patients with hyperacute cerebral infarction