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目的比较阿司匹林联合机械预防措施与低分子肝素预防全髋关节置换术后下肢深静脉血栓疗效的差异。方法 60例全髋关节置换患者,随机分为2组,阿司匹林组28例,低分子肝素组32例。术后在内服加味补阳还五汤的基础上,分别给予小剂量阿司匹林联合机械预防措施;低分子肝素,置换后根据双下肢彩色多普勒检查评估DVT形成情况,并观察治疗期间伤口出血情况。结果两组患者一般资料均衡可比,术后引流量差异有统计学意义。两组DVT发生率分别为10.7%、9.4%。结论在内服加味补阳还五汤的基础上,阿司匹林联合机械预防措施在预防全髋置换后下肢深静脉血栓的疗效上与低分子肝素相当,低分子肝素出血倾向明显,两种治疗方法都具有很好的疗效。
Objective To compare the efficacy of aspirin combined with mechanical prophylaxis and low molecular weight heparin in preventing lower extremity deep venous thrombosis after total hip arthroplasty. Methods Sixty patients undergoing total hip arthroplasty were randomly divided into two groups: 28 in aspirin group and 32 in low molecular weight heparin group. On the basis of oral administration of Modified Buyang Huanwu Decoction, low-dose aspirin combined with mechanical precaution was given respectively. Low-molecular-weight heparin was used to assess the formation of DVT according to the color Doppler examination of both lower extremities after replacement and to observe the wound bleeding during the treatment . Results The two groups of patients with a balanced general information, postoperative drainage volume difference was statistically significant. The incidence of DVT in both groups was 10.7% and 9.4% respectively. Conclusion On the basis of oral administration of BYHWD, aspirin combined with mechanical prophylaxis is equivalent to low molecular weight heparin in preventing lower extremity deep venous thrombosis after total hip replacement. Bleeding tendency of low molecular weight heparin is obvious. Both treatment methods have the following advantages Very good effect.