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目的应用Meta-analysis方法对国内9个有关A型行为与冠心病关系的病例对照研究进行综合定量分析。方法采用Fleiss模型和DerSimonianandNanLaird模型（D—L模型）处理数据。结果累积病例为1139人，对照为967人。采用Fleiss模型计算合并OR为2.32（95％CI1.93～2.79），D—L模型计算合并OR为2.32（95％CI1.80～2.99）。失效安全数远大于56。结论A型行为与冠心病有关，失效安全数大，可能的偏倚和混杂因素影响小。
Objective To apply the Meta-analysis method to conduct a comprehensive quantitative analysis of nine case-control studies on the relationship between type A behavior and coronary heart disease in China. Methods The data were processed using Fleiss model and DerSimonian and Nanlaird model (D-L model). Results The cumulative number of cases was 1139 and the control was 967. The combined odds ratio (OR) was 2.32 (95% CI 1.93-2.79) using the Fleiss model and 2.32 (95% CI 1.80-2.99) for the D-L model. The number of failure safety is much greater than 56. Conclusion Type A behavior is associated with coronary heart disease, with large number of failure safety and possible bias and confounding factors.