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患者男,55岁,于十八年前去海拔3850m~4200m高原工作,不久逐渐出现头昏、气促、心悸、腹胀、失眠、乏力、自发性齿龈出血及频泛性房早等症状,并经常感冒发热,疑高山反应,未引起注意。2年后返回平原,上述症状未缓解,因皮肤小破损出血不止,验RBC6.19×10~(12)/L,Hb168g/L、血小板500~600×10~9/L伴功能不良,血清总蛋白61g/l,γ-球蛋白8.9~10.5g/L,IgG7.~(12)g/L,IgA0.95g/L,IgM0.95g/L,淋巴细胞转化率58%,ch_(50)、160μ/ml,EKG房早,肝肾功能正常,骨髓穿刺示
The male patient, aged 55, worked at an altitude of 3850m ~ 4200m above sea level 18 years ago and soon developed dizziness, shortness of breath, heart palpitations, abdominal distension, insomnia, fatigue, spontaneous gingival bleeding and frequent morning sickness. Frequent colds and fever, suspected alpine reaction, did not attract attention. 2 years later returned to the plain, the above symptoms did not alleviate, due to minor skin damage bleeding more than test RBC6.19 × 10-12 / L, Hb168g / L, platelets 500-600 × 10-9 / L with dysfunction, serum The total protein 61g / l, γ-globulin 8.9-10.5g / L, IgG7. ~ (12) g / L, IgA 0.95g / L, IgM 0.95g / L, lymphocyte transformation rate of 58%, ch_ (50) , 160μ / ml, EKG room early, normal liver and kidney function, bone marrow puncture