寄生虫病与血液细胞学变化

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在患寄生虫病时,人体血液细胞动力学可出现明显的变化。最常受影响而增多的是嗜酸性粒细胞,有时单核细胞也可增多;有些寄生虫病也可出现红细胞和血小板系统的变化。常可出现明显贫血的寄生虫病中,在患疟疾时因疟原虫在红细胞内寄生并进行裂体增殖,破坏了大量红细胞。此外疟疾时脾脏吞噬红细胞的功能增强,抗原抗体复合物的作用促使红细胞被吞噬和破坏,以及骨髓造血功能受抑制等都是造成疟疾时出现贫血的原因。慢性疟疾脾机能亢进是产生贫血的主要原因,此时白细胞数和血小板数也减少。黑热病时出现的贫血与脾机能亢进有关,而与骨髓造血功能关系不大,近年来还证明免疫性溶血也是其重要的因素。因此,不仅红细胞数减少,粒细胞和血小板数也明显减少,前者往往先于贫血的出现。阿米巴肝脓肿病程稍久时 In patients with parasitic diseases, human blood cell kinetics can be significant changes. Most often affected by increased eosinophils, and sometimes mononuclear cells can also be increased; some parasitic diseases can also occur red blood cells and platelet system changes. Often there can be significant anemia in parasitic diseases, malaria parasites in malaria parasites and the proliferation of RBC proliferation, destruction of a large number of red blood cells. In addition, the phagocytosis of erythrocytes by spleens in malaria is enhanced. The role of antigen-antibody complexes in phagocytosis and destruction of erythrocytes as well as suppression of hematopoietic function in bone marrow are the causes of anemia when malaria is caused. Chronic malaria hypersplenism is the main cause of anemia, when the number of white blood cells and platelets also decreased. Anemia occurring in kala-azar relates to hypersplenism, but has little to do with the function of bone marrow hematopoiesis. In recent years, it has also been shown that immune hemolysis is also an important factor. Therefore, not only reduce the number of red blood cells, granulocytes and platelets also significantly decreased, the former often preceded the emergence of anemia. Amoeba liver abscess slightly longer duration
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