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药物性肝损伤是指人体暴露于常规剂量或高剂量药物后,因药物本身或其代谢产物对肝脏的直接毒性,或人体对药物或其代谢产物产生过敏或代谢特异质反应,而导致的肝脏损伤,是肝生化异常的常见原因之一。目前多种药物均可引起药物性肝损伤,常见的如解热镇痛药、抗生素、心脑血管疾病药等。患者怎么用药才能预防肝损伤?药物会否伤肝,除了药物本身及代谢物是否对肝有直接毒性外,另一个重要因素就是用法用量,每个人体质有所差异,如果超剂量用药也可能造成肝损伤。
Drug-induced liver injury refers to the human body after exposure to conventional or high-dose drugs, due to the drug itself or its metabolites on the liver’s direct toxicity, or the human body on the drug or its metabolites allergic or metabolic-specific reaction Liver damage is one of the common causes of abnormal liver biochemistry. At present a variety of drugs can cause drug-induced liver injury, common such as antipyretic analgesics, antibiotics, cardiovascular and cerebrovascular drugs. How patients use drugs to prevent liver damage? Drugs will hurt the liver, in addition to the drug itself and metabolites of the liver is not directly toxic, the other important factor is the amount of usage, each person’s physical differences, if overdosage medication may also result liver damage.