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目的:探讨施他宁(stilamin)、奥美拉唑(omeprazole)联合垂体后叶素(pituitrin)治疗老年上消化道出血的临床疗效。方法:收集我院2012年11月~2014年1月治疗的56老年例上消化道出血患者,随机分成观察组和对照组各28例,对照组给予垂体后叶素10U+0.9%氯化钠注射液20m L静推,同时奥美拉唑40mg加入生理盐水100ml中静脉滴注。观察组在对照组的基础上给予施他宁250μg加入0.9%氯化钠注射液20m L慢速静推。结果:观察组止血时间为(15.5±1.4)h,控制出血27例,出血控制率为96.4%,对照组止血时间为(38.2±3.8)h,观察组治愈22例,显效4例,有效1例,无效1例,总有效率为96.4%,对照组治愈12例,显效5例,有效3例,无效8例,总有效率为71.4%,两组比较有统计学意义(P<0.05)。结论:施他宁、奥美拉唑联合垂体后叶素治疗上消化道出血止血时间短,临床疗效好,值得临床推广。
Objective: To investigate the clinical effects of stilamin, omeprazole combined with pituitrin in the treatment of senile upper gastrointestinal bleeding. Methods: A total of 56 elderly patients with upper gastrointestinal bleeding who were treated in our hospital from November 2012 to January 2014 were randomly divided into observation group (28 cases) and control group (28 cases). The control group was given pituitrin 10 U + 0.9% sodium chloride Injection 20m L static push, at the same time omeprazole 40mg added saline 100ml intravenous infusion. The observation group was given shituning 250μg on the basis of the control group with 0.9% sodium chloride injection 20m L slow static push. Results: The bleeding time in the observation group was (15.5 ± 1.4) h, the bleeding was controlled in 27 cases, the bleeding control rate was 96.4%, the control group was (38.2 ± 3.8) h, the observation group was cured in 22 cases, markedly effective in 4 cases, effective 1 In the control group, 12 cases were cured, 5 cases were markedly effective, 3 cases were effective, 8 cases were ineffective and the total effective rate was 71.4%. The two groups were statistically significant (P <0.05) . Conclusion: The combination of Sitatin and Omeprazole combined with pituitrin in the treatment of upper gastrointestinal hemorrhage has a short time to stop bleeding and has good clinical curative effect. It is worthy of clinical promotion.