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目的分析丁苯酞与负荷剂量抗血小板药物联合治疗急性脑梗死的临床效果。方法 86例急性脑梗死患者,随机分为观察组与对照组,各43例。对照组给予100 mg阿司匹林治疗,观察组给予丁苯酞氯化钠注射液联合负荷量阿司匹林、氯匹格雷各300 g治疗,比较两组治疗效果。结果观察组总有效率为90.7%高于对照组的67.4%,差异有统计学意义(P<0.05);治疗前,两组患者神经功能缺损评分(NIHSS)比较,差异无统计学意义(P>0.05);治疗后,观察组NIHSS评分明显低于对照组,差异有统计学意义(P<0.05)。结论丁苯酞与负荷剂量抗血小板药物联合治疗急性脑梗死的临床疗效显著,值得在临床上推广。
Objective To analyze the clinical effect of combination of butylphthalide and loaded antiplatelet drugs in the treatment of acute cerebral infarction. Methods A total of 86 patients with acute cerebral infarction were randomly divided into observation group and control group, with 43 cases in each group. The control group was treated with 100 mg aspirin. The observation group was treated with sodium butyrate and sodium chloride injection in combination with 300 g aspirin and clopidogrel respectively. The therapeutic effects were compared between the two groups. Results The total effective rate in the observation group was 90.7%, which was significantly higher than that in the control group (67.4%, P <0.05). There was no significant difference in NIHSS between the two groups before treatment > 0.05). After treatment, the NIHSS score in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Butylphthalide and loading dose of antiplatelet drugs in the treatment of acute cerebral infarction clinical significant effect, it is worth in the clinical promotion.