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８０年代初期，新型的β羟基β甲基戊二酰辅酶Ａ（ＨＭＧＣｏＡ）还原酶抑制剂的问世是降脂药的一大进展，其作用强于其他降脂药。此类药不仅抑制胆固醇的内源性合成，而且加速其代谢，其中以辛伐他丁（ｓｉｍｖａｓｔａｔｉｎ，又名舒降之）最有效。本研究对小剂量辛伐?
In the early 1980s, the advent of a new type of β-hydroxy-β-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor was a major progress of lipid-lowering drugs, its effect is stronger than other lipid-lowering drugs. Such drugs not only inhibit the endogenous synthesis of cholesterol, but also to speed up its metabolism, of which simvastatin (also known as comfortable down) the most effective. This study of small doses of simvastatin?