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目的:探讨磁共振成像(MRI)对颈动脉狭窄患者动脉狭窄程度及脑功能变化的评估。方法:选取2016年1月-2016年12月于宁波市医疗中心李惠利医院神经内科就诊的单侧颈动脉狭窄患者53例作为研究对象。以数字减影血管造影(DSA)作为评估颈动脉狭窄患者中动脉狭窄程度的金标准,比较MRI与DSA评估动脉狭窄程度的一致性。并通过功能MRI检测狭窄侧与对侧脑功能差异。结果:DSA检测轻度狭窄32例,中度狭窄11例,重度狭窄8例,完全闭塞2例,MRI检测轻度狭窄30例,中度狭窄12例,重度狭窄9例,完全闭塞2例,MRI检测和DSA检测的一致性良好(Kappa=0.903,P<0.001);颈动脉狭窄患者狭窄侧额叶FA值明显低于对侧(t=-2.539,P=0.013)。结论:MRI可有效评估颈动脉狭窄患者动脉狭窄程度,且对脑功能变化有一定的评估价值。
Objective: To evaluate the effect of magnetic resonance imaging (MRI) on the degree of stenosis and brain function in patients with carotid artery stenosis. Methods: From January 2016 to December 2016, 53 patients with unilateral carotid artery stenosis treated in the Department of Neurology, Li Huili Hospital, Ningbo Medical Center were selected as the research object. Digital subtraction angiography (DSA) was used as the gold standard for assessing the degree of stenosis in patients with carotid artery stenosis. MRI and DSA were used to evaluate the consistency of arterial stenosis. Functional MRI was used to detect differences in function between the stenosis and the contralateral brain. Results: There were 32 mild stenosis, 11 moderate stenosis, 8 severe stenosis, 2 complete occlusion, 30 mild stenosis by MRI, 12 moderate stenosis, 9 severe stenosis, 2 complete occlusion, The consistency of MRI and DSA was good (Kappa = 0.903, P <0.001). The value of FA in stenotic side of carotid artery stenosis was significantly lower than that of contralateral side (t = -2.539, P = 0.013). Conclusion: MRI can effectively assess the degree of arterial stenosis in patients with carotid artery stenosis, and have certain value in evaluating the changes of brain function.