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世界范围内,恶性肿瘤已成为严重危害人类健康的疾病,治疗恶性肿瘤的难点是肿瘤的复发和血道淋巴道转移[1]。但人类对淋巴系统的研究远没有血管系统的深入,究其原因是缺乏有效的能鉴定淋巴管的特异性标记物。淋巴管内皮细胞标记物D2-40的发现和应用无疑为研究肿瘤相关淋巴管生成和肿瘤的淋巴管播散机制提供了新思路。文章就D2-40的生物学特性及在胃肠道淋巴管生成中的研
Worldwide, malignant tumors have become serious diseases that endanger human health. The difficulty of treating malignant tumors is tumor recurrence and hematogenous lymph node metastasis [1]. However, the study of human lymphatic system far from the depth of the vascular system, the reason is the lack of effective identification of specific markers of lymphatic vessels. The discovery and application of lymphatic endothelial cell marker D2-40 undoubtedly provided a new idea for studying lymphangiogenesis of tumor and lymphatic vessel dissemination mechanism of tumor. Article on the biological characteristics of D2-40 and gastrointestinal Lymphangiogenesis research