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实验结果表明,壮腰健肾口服液能增加棉油性大鼠精虫数量;去势小鼠及正常大鼠性器官的重量;增加大鼠血浆睾丸酮含量。提高小鼠对热致痛反应的痛阈值及醋酸所致扭体反应出现时间,明显抑制二甲苯性小鼠耳部炎症反应,醋酸性小鼠腹腔伊文思蓝渗出量、大鼠棉球肉芽肿及甲醛性大鼠后足踝关节炎症反应。明显延长小鼠在高温、低温负重情况下的游泳时间及常压缺氧情况下的生存时间,降低大鼠肾上腺维C含量。最大耐受量实验表明,小鼠一次口服壮腰健肾口服液的最大耐量为临床一次用量的2000倍。
The experimental results show that Zhuangyao Jianshen Oral Liquid can increase the number of cottonseed rat spermatozoa; the weight of sexual organs in castrated mice and normal rats; and increase the plasma testosterone content in rats. Increased the pain threshold of heat-induced pain in mice and the appearance of writhing response caused by acetic acid, significantly inhibited the ear inflammatory reaction in xylene mice, Evans blue exudation in abdominal cavity of acetic acid mice, cotton pellets of rats Swollen and formalin-induced inflammatory reaction in hindpaw joints of rats. It significantly prolongs the swimming time of mice under high temperature and low temperature load conditions and the survival time under normobaric hypoxia, and reduces the content of adrenal V-C in rats. The maximum tolerated dose experiment showed that the maximum tolerance of a single oral administration of Zhuangyao Jianshen Oral Liquid was 2,000 times the clinical dose.