论文部分内容阅读
目的:探讨 Leksell-C 型伽玛刀治疗垂体瘤的方法和疗效。方法:采用 Leksell-C 型伽玛刀进行治疗垂体瘤51例。50%～70%等剂量曲线包绕肿瘤,周边剂量12～35 Gy,中心剂量24～70 Gy,小准直器、多靶点剂量计划设计。结果:随访4～18个月,临床症状改善或消失21例(55%),不变17例(45%),影像学复查缩小8例(21%),不变23例(61%)。内分泌检查 PRL 下降13例,不变3例,GH 下降2例,ACTH 1例,FSH 不变1例。随访38例中目前尚无垂体功能低下、视力下降等并发症出现。结论:利用 Leksell-C 型伽玛刀治疗垂体瘤是安全、有效的。
Objective: To investigate the method and efficacy of Leksell-C gamma knife in the treatment of pituitary tumor. Methods: 51 cases of pituitary tumor were treated with Leksell-C gamma knife. 50% ~ 70% isodose curves surrounding the tumor, the peripheral dose of 12 ~ 35 Gy, the central dose of 24 ~ 70 Gy, small collimator, multi-target dose planning design. Results: After 4 to 18 months of follow-up, clinical symptoms improved or disappeared in 21 cases (55%), unchanged in 17 cases (45%), imaging reduced in 8 cases (21%) and unchanged in 23 cases (61%). Endocrine examination PRL decreased in 13 cases, unchanged in 3 cases, GH decreased in 2 cases, ACTH in 1 case, FSH unchanged in 1 case. No follow-up of 38 cases of pituitary dysfunction, decreased visual acuity and other complications appear. Conclusion: Leksell-C gamma knife treatment of pituitary tumors is safe and effective.