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目的:探讨蒙古族细菌性阴道病妇女与健康妇女阴道乳杆菌属内乳杆菌分布种类及产生过氧化氢(H2O2)能力的差异。方法:以102例蒙古族BV患者为病例组,98例正常蒙古族妇女为对照组,检查阴道乳酸杆菌菌种分布,测定阴道乳酸杆菌产H2O2能力及鉴定阴道内乳杆菌种类。结果:两组乳酸杆菌检出率分别为21.6%(22/102)、75.5%(74/98),两组比较差异有统计学意义(χ2=21.016,P=0.001);两组乳酸杆菌菌种分布差异无统计学意义(P>0.05),均以卷曲乳杆菌、加氏乳杆菌、嗜酸乳杆菌和干酪乳杆菌为优势菌;H2O2阳性乳酸杆菌分离率分别为27.3%(6/22)、75.7%(56/74),两者相比差异有统计学意义(χ2=4.528,P<0.050)。结论:蒙古族BV患者与蒙古族健康妇女相比阴道乳杆菌检出率明显下降;阴道产过氧化氢乳杆菌分离率及整体产过氧化氢能力显著下降;蒙古族BV患者与正常蒙古族妇女阴道乳杆菌种分布相似。
Objective: To investigate the distribution of Lactobacillus in vaginal Lactobacillus between Mongolian women with bacterial vaginosis and healthy women and their ability to produce hydrogen peroxide (H2O2). Methods: 102 Mongolian patients with BV were selected as the case group and 98 normal Mongolian women as the control group. The distribution of Lactobacillus vaginalis strains was examined. The ability of Lactobacillus vaginalis to produce H2O2 was determined and the types of lactobacilli in vagina were identified. Results: The detection rates of Lactobacilli in two groups were 21.6% (22/102) and 75.5% (74/98), respectively, with significant difference between the two groups (χ2 = 21.016, P = 0.001) (P> 0.05). The dominant strains were Lactobacillusfurfiens, Lactobacillus gasseri, Lactobacillus acidophilus and Lactobacillus casei. The separation rates of H2O2-positive Lactobacillus were 27.3% (6/22 ) And 75.7% (56/74), respectively. There was significant difference between them (χ2 = 4.528, P <0.050). CONCLUSION: The detection rate of Lactobacillus vaginalis in Mongolian patients with BV is significantly lower than that in healthy Mongolian women. The isolation rate of Lactobacillus perchlorate and the ability of producing hydrogen peroxide in the vagina are significantly decreased. The Mongolian patients with BV are significantly different from the normal Mongolian women Lactobacillus vaginalis distribution is similar.