Study on pathogenic genes of dwarfism disease by next-generation sequencing

• 作 者: Lv-Lv Yang Shi-Shan Liang
• 机 构: DepartmentofPediatrics
• 出 处: 世界临床病例杂志
• 发表日期: 2021年7期
• 关键词: DWARFISM Next-generation sequencing Pathogenicity variability Growth hormone THE
• 基金项目: Quanzhou Science and Technology Bureau,No.2018Z072

BACKGROUND There are many factors that lead to dwarfism,and the mechanism has not yet been elucidated.Next-generation sequencing may identify candidate-related gene mutations,which may clarify the molecular cause.AIM To analyze genetic variation by using