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本文采用双单克隆抗体夹心法ELISA对80例病毒性肝炎患者的血清白细胞介素-6(IL-6)的水平进行了检测,结果发现各型病毒性肝炎患者血清IL-6水平均显著高于健康对照组,且以慢性肝炎(中度)升高尤为明显,并且IL-6水平与ALT及BIL呈正相关,提示IL-6可能参与肝细胞的自身免疫反应,并能反映肝脏病变的活动状况。
In this paper, double monoclonal antibody sandwich ELISA was used to detect the level of serum interleukin-6 (IL-6) in 80 patients with viral hepatitis and found that serum IL-6 levels were significantly higher in patients with various types of viral hepatitis IL-6 was positively correlated with ALT and BIL, suggesting that IL-6 may be involved in the autoimmune response of hepatocytes and reflect the activity of liver lesions situation.