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用利福平、异烟肼、乙胺丁醇在26名未卧床的男性结核病患者(年龄49.5±9.9岁,体重63.5±9.4kg)体中进行药代动力学测定。给药方式为:利福平;利福平+异烟肼;利福平+乙胺丁醇;异烟肼;异烟肼+乙胺丁醇;利福平+异烟肼+乙胺丁醇。药物(?)量:异烟肼300mg(4.8±0.7mg·kg);利福平600mg(9.5±1.2mg·kg);乙胺丁醇800mg(12.5±1.6mg·kg)。患者经一夜禁食以后在次日早上空腹服入,服药后两小时才可摄食。
Rituximab, isoniazid, and ethambutol were tested for pharmacokinetics in 26 untreated male tuberculosis patients (age 49.5 ± 9.9 years, body weight 63.5 ± 9.4 kg). Rifampin + isoniazid; Rifampicin + Ethambutol; Isoniazid; Isoniazid + Ethambutol; Rifampin + Isoniazid + Ethambutol alcohol. Drug (?) Quantity: Isoniazid 300mg (4.8 ± 0.7mg · kg); Rifampicin 600mg (9.5 ± 1.2mg · kg); Ethambutol 800mg (12.5 ± 1.6mg · kg). The patient was fasted on the morning of the following morning after fasting for one night and two hours after taking the medicine.