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目的探讨老年高血压脑梗死患者颈动脉粥样硬化斑块稳定性与动态动脉硬化指数之间的关系。方法选择98例年龄>60岁高血压伴动脉硬化性脑梗死患者进行颈动脉超声检查,诊断斑块性质,并同时对入选者行24h动态血压监测计算出动态动脉硬化指数。结果 17例未检出斑块,45例检出稳定斑块,36例检出不稳定斑块。颈动脉粥样硬化板块检出率82.65%(81/98)。无斑块、不稳定斑块及稳定斑块组间动态动脉硬化指数差异有统计学意义。(F为49.026,P<0.10)不稳定斑块组动态动脉硬化指数高于稳定斑块组和无斑块组(P<0.05),稳定斑块组动态动脉硬化指数高于无斑块组(P<0.05)。结论动态动脉硬化指数可反映颈动脉粥样硬化斑块的稳定性。
Objective To investigate the relationship between the stability of carotid atherosclerosis plaque and dynamic arteriosclerosis index in elderly patients with hypertensive cerebral infarction. Methods Ninety-eight patients with hypertension and arteriosclerotic cerebral infarction were enrolled in this study. Carotid ultrasonography was performed to diagnose the plaque quality. At the same time, dynamic arterial stiffness index was calculated for 24 h ambulatory blood pressure monitoring. Results 17 cases did not detect plaque, 45 cases detected stable plaque, 36 cases detected unstable plaque. Carotid atherosclerosis plate detection rate was 82.65% (81/98). The difference of dynamic arteriosclerosis index between no plaque, unstable plaque and stable plaque group was statistically significant. (F = 49.026, P <0.10). The dynamic arteriosclerosis index in unstable plaque group was higher than that in stable plaque group and non-plaque group (P <0.05). The dynamic arterial stiffness index in stable plaque group was higher than that in non-plaque group P <0.05). Conclusion The dynamic arteriosclerosis index can reflect the stability of carotid atherosclerotic plaques.