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一、关于淋巴细胞的进展近十几年来,随着免疫学、酶学、细胞生物学、细胞遗传学以及电镜技术等的发展,人们对淋巴细胞的来源、结构与功能有了进一步的认识,并将其分成若干亚群。Gowans首先提出淋巴细胞具有免疫功能。他观察到淋巴细胞在体内可以再循环,接触抗原刺激后,产生母细胞化,进一步分化增殖。这个发现否定了过去五十年一直认为淋巴细胞只是短命的、终末的细胞的观点。目前发现来自骨髓的淋巴样干细胞,通过胸腺作用分化增殖为具有免疫功能的T淋巴细胞;通过骨髓和肠道淋巴结的作用,可以分化增殖为B淋巴细胞。遗传因素对免疫反应影响的研究,推动
First, on the progress of lymphocytes Over the past decade, with the development of immunology, enzymology, cell biology, cytogenetics and electron microscopy, people have a further understanding of the origin, structure and function of lymphocytes, And it is divided into several subgroups. Gowans first proposed that lymphocytes have immune function. He observed that lymphocytes can be recycled in the body and, after exposure to antigenic stimuli, produce blastocysts that further differentiate and proliferate. This finding dismisses the belief that lymphocytes have been short-lived, terminal cells for the past fifty years. It has been found that bone marrow-derived lymphoid stem cells differentiate and proliferate into immune-competent T lymphocytes through the thymus; they can differentiate and proliferate into B lymphocytes through the action of bone marrow and intestinal lymph nodes. Study on the influence of genetic factors on immune response