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本文报告用HAP-DOM方案治疗急性非淋巴细胞白血病13例。结果:获得完全缓解CR)10例,CR率达76.9%;治疗后骨髓增生程度低下容易达到CR;化疗后外周血白细胞数低下相当于骨髓有核细胞增生低下,二者关系基本是平行的;二个分方案交替使用不易产生抗药性,从而进一步提高缓解率;可以缩短病员的治疗时间;毒性反应较轻。
This article reports 13 cases of acute non-lymphocytic leukemia treated with HAP-DOM regimen. Results: Complete CR was achieved in 10 cases, the CR rate was 76.9%. The degree of myeloproliferation was easily decreased after CR treatment. The number of peripheral blood leukocytes after chemotherapy was equivalent to the low proliferation of bone marrow nucleated cells, the relationship between them was basically parallel. Two sub-programs alternating use is not easy to produce resistance, thereby further improving the remission rate; can shorten the treatment of patients; toxicity less.