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近年来,国内外采用低功率He—Ne激光穴位照射治疗某些Ⅰ型变态反应性疾病,取得满意的近期疗效,已有不少报导,与其它治疗方法相比,有一定的优越性,但对其作用原理探讨颇少。我们选择动物皮肤过敏反应(PCA)的试验方法,(Passive Cutaneous Anaphylaxis Reaction),来观察He—Ne激光穴位照射对Ⅰ型变态反应的影响。实验方法将羊毛脂与石腊油以1:4比例配制成不完全弗氏佐剂,每毫升不完全弗氏佐剂加入5毫克天花粉(上海生化制药厂)制成混悬液。按每公斤1毫克天花粉的剂量,将上混悬液分别注射在体重2.0～2.5公斤8只健康雄性家兔的后肢脚爪掌心,随机分为激光、对照两组,每组4只。激光组用8毫瓦He—Ne
In recent years, low-power He-Ne laser acupoint irradiation has been used to treat certain type I allergic diseases at home and abroad, and satisfactory near-term efficacy has been achieved. There have been many reports, and there are certain advantages compared with other treatment methods, but there are certain advantages. The principle of its action is rarely discussed. We chose the Passive Cutaneous Anaphylaxis Reaction (PCA) test method to observe the effect of He-Ne laser acupoint irradiation on type I allergic response. The experimental method was to formulate lanolin and paraffin oil in incomplete Freund’s adjuvant in a ratio of 1:4, and add 5 mg of trichosanthin (Shanghai Biochemical Pharmaceutical Factory) to make a suspension per ml of incomplete Freund’s adjuvant. According to the dosage of 1 mg trichosanthin per kilogram, the upper suspension was injected into the hindpaw palms of 8 healthy male rabbits weighing 2.0-2.5 kg and randomly divided into laser and control groups, 4 in each group. 8 mW He-Ne for Laser Group