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目的分析青春期卵巢肿瘤的临床特征,探讨其诊断和治疗方法。方法回顾性分析200例10～20岁青春期卵巢肿瘤患者资料。其中,病理确诊上皮性肿瘤39例,生殖细胞肿瘤154例,性索间质肿瘤5例,转移性肿瘤1例,卵巢平滑肌瘤1例。结果 13例恶性生殖细胞肿瘤及2例中分化支持间质细胞瘤,行手术加术后化疗。1例转移性肿瘤单纯进行化疗后自动出院。结论青春期卵巢肿瘤大多为良性,且生殖细胞肿瘤占多数。除非证实肿瘤为恶性,否则应尽量保留卵巢;如对侧卵巢外观无异常,不应常规活检或楔形切除。卵巢恶性生殖细胞肿瘤可以行保留生育功能的术式。
Objective To analyze the clinical features of adolescent ovarian tumors and to explore its diagnosis and treatment. Methods A retrospective analysis of 200 cases of adolescent ovarian cancer patients aged 10 to 20 years. Among them, pathologically diagnosed 39 cases of epithelial tumors, germ cell tumors in 154 cases, 5 cases of sex cord stromal tumors, metastatic tumors in 1 case, ovarian leiomyoma in 1 case. Results Thirteen cases of malignant germ cell tumor and two cases of moderately differentiated stromal cell tumor were treated with operation and postoperative chemotherapy. One case of metastatic tumor was discharged after chemotherapy alone. Conclusion Most adolescent ovarian tumors are benign, and the majority of germ cell tumors. Unless the malignancy of the tumor is confirmed, the ovary should be preserved as much as possible. If there is no abnormal appearance of the contralateral ovary, routine biopsy or wedge resection should not be performed. Malignant ovarian germ cell tumors can be retained reproductive function of the surgical procedures.