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旭川医科大学消化器外科的水户迪郎教授等的研研小组,在世界上首次将肝细胞的一部分自家移植到脾脏,而使脾脏代行肝脏机能。肝脏是人体内脏中唯一具有旺盛再生能力的脏器。例如,即使切除肝脏四分之三也能在约三个月后增生复原。水户教授等就是否可以利用肝脏的这一性质,自家移植于其他部位并增殖,从而长期再现肝脏机能的可能性进行了不懈地研究。在对大白鼠的实验中,移植于同一个体脾脏的肝细胞约一年半增殖到相当于脾脏的80%左右大小并替代了代谢、解毒等原肝脏机能的15%。用猿猴也获得了
Asahikawa Medical University Department of Gastroenterology, Professor Dmitry Mito and other research groups in the world for the first time part of the liver cells transplanted to the spleen, leaving the spleen to perform liver function. The liver is the only organ in the body that has strong regenerative capacity. For example, even three-quarters of the liver is resected to proliferate after about three months. Mito and others have been working tirelessly on the possibility of using this property of the liver, transplanting it to other sites and multiplying it, and thereby reproducing the liver in the long term. In experiments on rats, the hepatocytes transplanted in the spleen of the same individual proliferated to approximately 80% of the spleen in approximately one and a half years and replaced 15% of the original liver function such as metabolism and detoxification. Also obtained with apes