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治疗伤寒传统首选氯霉素。但由于近年来临床疗效减退,耐药菌株大量出现,毒性危象不断增多,为了重新评价氯霉素以及进一步探索我地伤寒常用的几种抗菌药物的确切疗效,现将1984年6月—1986年10月收治的全部血培养证实的123例伤寒病人,使用抗生素的疗效及菌株体外试验测定结果分析如下。临床资料细菌培养药敏试验,采用纸片法,对9种药物敏感度见表1。治疗分组,分为A、B、C、D4组,其中D组为混合治疗组。治疗情况:A组38例,选用了胺卡那与庆大霉素联用,剂量:前者0,4克,IM,bid,后者24万/日,静脉滴注;B组37例,单
Traditional treatment of typhoid chloramphenicol preferred. However, in recent years, due to the diminished clinical efficacy, a large number of drug-resistant strains appear, toxic crisis continues to increase, in order to re-evaluate the chloramphenicol and to further explore the exact efficacy of several antimicrobial drugs commonly used in typhoid, now 1984-86 In October of all blood culture confirmed 123 cases of typhoid patients, the efficacy of antibiotics and strains in vitro test results are as follows. Clinical data bacterial culture susceptibility testing, using the paper method, the sensitivity of 9 drugs in Table 1. Treatment group, divided into A, B, C, D4 group, of which D group for the mixed treatment group. Treatment: A group of 38 patients, the choice of amine card with gentamicin, the dose: the former 0,4 g, IM, bid, the latter 240,000 / day, intravenous infusion; B group of 37 patients, single