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自1948年在临床上开始应用考的松(Cortisone)以来,肾上腺皮质激素类药物治疗疾病的种类很多,这类激素长期应用时,常产生副作用。因此,人们努力寻找效力强、选择性高而副作用少的类固醇皮质激素。一、化学结构与药理作用的关系
Cortisone has been used clinically since Cortisone since 1948. Corticosteroids are used to treat a wide variety of diseases. These hormones often cause side effects when used on a long-term basis. Therefore, people are trying to find effective steroid corticosteroids with high selectivity and few side effects. First, the relationship between chemical structure and pharmacological effects