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1 血管紧张素转换酶(ACE)活性:结节病及矽肺、鈹肺时血清中ACE 活性升高。用荧光抗体法等对结节病研究证实,由类上皮细胞构成肉芽肿,在活动期时血清ACE 活性高于静止期,当出现肺门淋巴结肿大时,升高更明显,甚至比肺野病变增加或出现肺外病变时都更明显。而出现眼部或皮肤病变时,其活性升高并不明显。结节病时血清ACE 活性升高与病变的进展有相关性,但与预后的相关性不明显。在自发性气胸、肺炎、肺癌时血清ACE 活性并不升高,其原因之一可能是由于毛细血管床减少,ACE
1 angiotensin converting enzyme (ACE) activity: sarcoidosis and silicosis, beryllium lung serum ACE activity increased. Fluorescent antibody method for sarcoidosis studies confirmed that by the epithelial cells to form granulomas, serum ACE activity in the active period was higher than the quiescent period, when hilar lymph node enlargement, the more obvious increase, even more than the lung field Increased lesions or extrapulmonary lesions are more obvious. Occur in the eyes or skin lesions, the activity is not obvious. Serum ACE activity in sarcoidosis and the progress of the disease have a correlation, but the prognosis is not obvious. In spontaneous pneumothorax, pneumonia, lung cancer serum ACE activity does not increase, one of the reasons may be due to reduced capillary bed, ACE